Fellow ex-Mamelodi Sundowns forward Leonardo Castro will also miss the game against Usuthu.
Chiefs announced: “Khama Billiat has a cracked leg bone and will be out for two months. Leonardo Castro has an abdominal strain and will be unavailable for the AmaZulu game.
“[Midfielder] Kearyn Baccus is now back from injury and is available for selection. [Right-back] Reeve Frosler is now running on the pitch. We will update you on his progress.”